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Oral Versus Intravenous Acetaminophen within an Enhanced Recovery after Surgery Protocol in Colorectal Surgery
What is already known:
Multimodal analgesia is an essential part of a successful ERAS programme, in particular simple analgesics such as acetaminophen or paracetamol.
What this paper adds:
All patients underwent colorectal resection within a comprehensive ERAS programme. All had a multimodal analgesic regimen, but with the only difference being either intravenous or oral paracetamol / acetaminophen. There was no overall difference in pain scores. But the iv group received significantly less oral morphine equivalents, and were also significantly less likely to receive opioid patient controlled analgesia. However whilst the findings were interesting, this was a retrospective review performed in a single centre. It also goes against the findings of a recent meta-analysis which showed no difference between the two routes.
Chris Jones, Guildford. @chrisnjones.
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