Colorectal

Colorectal

The thoughts and theories about enhanced recovery all started in colorectal surgery. This was not a coincidence since the average age at diagnosis with colorectal cancer is generally high and most of the patients are scheduled for major surgery with a high risk of complications. Due to the lack of congruence in perioperative care across sites, the unsatisfactory recovery rates, and diverse quality in terms of reporting outcomes, there was a need for new perioperative regimens, other than the currently practiced traditional perioperative care.

Inspired by the early work of Henrik Kehlet, Denmark, showing significantly improved recovery after colorectal surgery, the enhanced recovery after surgery (ERAS) study group collaboration was established in 2000. The international ERAS database (EIAS), the concept of using standardized interventions, the way to calculate compliance and the structure of conducting guidelines, all has evolved from the work with colorectal surgery.

The first ERAS guideline in colorectal surgery was published in 2005 (1). The following guidelines 2012 were divided in colonic (2) and rectal surgery (3), where the two surgical modalities were reunited in the last published guidelines 2018 (4).
The way of conducting guidelines has changed over the years. If the first guideline was based on literature review and expert opinions, the latest guideline underwent a rigorous framework, including grading of evidence according to the GRADE-system, on how to conduct guidelines. In 2020, guidelines for guidelines in ERAS society was published in British Journal of surgery open (5).

When comparing ERAS protocols with traditional care in colorectal surgery, ERAS significantly reduce the risk for postoperative morbidity with 48% (6) and median length of stay in hospital, 2.5 days (7). However, current evidence in favor of the ERAS protocol applies for the whole protocol and not for every single item within it. Thus, the evidence base behind each item within the protocol is constantly changing depending on which new evidence are published.

One of the main purposes with this part of the website is to constantly review and present new publications which may affect the current state of evidence behind items within the ERAS protocol, but also to present news that may be of general interest in association with colorectal surgery and ERAS.

Colorectal References

Expert Reviews

Contacts

Guideline Co-Chair

Associate Professor Ulf Gustafsson (Sweden)

Ulf is a Senior consultant surgeon, specializing in colorectal surgery, laparoscopic and robotic surgery, Dept of Surgery, Danderyd’s Hospital, Stockholm, Sweden. He is Research group leader, Department of Clinical…

Mattias Soop (Sweden)

I am a surgeon specialising in the management of inflammatory bowel disease and intestinal failure. I completed general surgical training and a PhD in surgery in 2004 at the Karolinska…